Name | Wilms tumor and (C:U) |
Description | RNA editing of A3A induces changes in WT1 mRNA which correspond to driver cancer mutations suggests a potential role for this novel modification in cancer mutagenesis |
Related RNA reaction | C:U |
Found in RNA | mRNA |
Modified Transcript | WT1 |
Mapping Technology | Sanger sequencing |
Quantification techniques | qRT-PCR |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
APOBEC3A | apolipoprotein B mRNA editing enzyme catalytic subunit 3A | tumor-suppressor/oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1118 | APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts. | Ahmadreza Niavarani | PLoS One | [details] | 25807502 | 10.1371/journal.pone.0120089 |