Summary:

NameAcute Myeloid Leukemia (C:U)
DescriptionRNA editing of A3A induces changes in WT1 mRNA which correspond to driver cancer mutations suggests a potential role for this novel modification in cancer mutagenesis
Related RNA reactionC:U
Found in RNAmRNA
Modified TranscriptWT1
Mapping TechnologySanger sequencing
Quantification techniquesqRT-PCR

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A tumor-suppressor/oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1118 APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts. Ahmadreza Niavarani PLoS One [details] 25807502 10.1371/journal.pone.0120089

Copyright © Genesilico - All rights reserved
If you have any advice or suggestions for corrections or improvements, please contact: Andrea Cappannini - lp.vog.bcmii@ininnappaca