Modomics - A Database of RNA Modifications

Summary:

NameType 2 Diabetes (A:I)
DescriptionRNA editing, on different transcripts, promotes the disease risk and is closely associated with type 2 Diabetes
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptARPIN, pri-mir-27b, mir-605
Mapping TechnologyRNA-seq
Quantification techniquesedQTLs

Enzymes connected to Type 2 Diabetes:

Acronym Full name Enzyme Role Organism Comment
Exact modification enzyme yet to be verified. One or more ADAR enzymes involved, putatively.

Publications:

ID Title Authors Journal Details PubMed Id DOI
1125 Global analysis of A-to-I RNA editing reveals association with common disease variants. Raili Ermel,Katyayani Sukhavasi,Rajeev Jain,Anamika Jain,Christer Betsholtz,Chiara Giannarelli,Jason C Kovacic,Arno Ruusalepp,Josefin Skogsberg,Ke Hao,Eric E Schadt, PeerJ [details] 29527417 10.7717/peerj.4466