Modomics - A Database of RNA Modifications

Summary:

NameUrothelial carcinoma of the bladder (UCB) (C:m5C)
DescriptionNSUN2 and YBX1 stabilize the oncogene mRNA of the oncogene HDGF that mediates UCB pathogenesis in human
Related RNA reactionC:m5C
Found in RNAmRNA
Modified TranscriptHDGF
Mapping TechnologyBisulphite-seq
Quantification techniquesUHPLC–MRM–MS/MS

Enzymes connected to Urothelial carcinoma of the bladder (UCB):

Acronym Full name Enzyme Role Organism Comment
NSUN2 NOP2/Sun RNA methyltransferase 2 oncogene Homo sapiens
YBX1 Y-box binding protein 1 oncogene Homo sapiens

Publications:

ID Title Authors Journal Details PubMed Id DOI
1126 5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs Chen X, Li A, Sun BF, Yang Y, Han YN, Yuan X, Chen RX, Wei WS, Liu Y, Gao CC, Chen YS, Zhang M, Ma XD, Liu ZW, Luo JH, Lyu C, Wang HL, Ma J, Zhao YL, Zhou FJ, Huang Y, Xie D, Yang YG. Nat Cell Biol . [details] 31358969 10.1038/s41556-019-0361-y