Summary:

NameUrothelial carcinoma of the bladder (UCB) (C:m5C)
DescriptionNSUN2 and YBX1 stabilize the oncogene mRNA of the oncogene HDGF that mediates UCB pathogenesis in human
Related RNA reactionC:m5C
Found in RNAmRNA
Modified TranscriptHDGF
Mapping TechnologyBisulphite-seq
Quantification techniquesUHPLC–MRM–MS/MS

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
NSUN2 NOP2/Sun RNA methyltransferase 2 oncogene Homo sapiens
YBX1 Y-box binding protein 1 oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1126 5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs Chen X Nat Cell Biol . [details] 31358969 10.1038/s41556-019-0361-y

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