Modomics - A Database of RNA Modifications

Summary:

NameBreast cancer (A:m6A)
DescriptionExpression levels of writers, readers and erasers differs between cancer cell lines; no association of the expression levels of METTL3, YTHDF1, WTAP with overall survival was found; HNRNPA2B1 over-expression is associated with poorer overall survival and promotes endocrine resistance;
Related RNA reactionA:m6A
Found in RNAmiRNA
Modified Transcriptmultitude of miRNAs
Mapping TechnologyNone
Quantification techniquesNone

Enzymes connected to Breast cancer:

Acronym Full name Enzyme Role Organism Comment
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
987 HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells. Carolyn M Klinge Sci Rep [details] 31263129 10.1038/s41598-019-45636-8