| Name | Depression disorder (C:U) |
| Description | RNA editing inhibits the enzymatic activity of TPH2 splice variants. Deregulated alternative splicing and RNA editing are involved in the etiology of psychiatric diseases, such as suicidal behavior. |
| Related RNA reaction | C:U |
| Found in RNA | mRNA |
| Modified Transcript | TPH2b |
| Mapping Technology | exone sequencing |
| Quantification techniques | HPLC |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| ADARB1 | Double-stranded RNA-specific editase 1 | None | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1008 | Alternative splicing and extensive RNA editing of human TPH2 transcripts. | Paul Hammer,Maria Walther,Nils Paulmann,Andreas Büttner,Wolfgang Eisenmenger,Thomas C Baghai,Cornelius Schüle,Rainer Rupprecht,Michael Bader,Brigitta Bondy,Peter Zill,Josef Priller, | PLoS One | [details] | 20126463 | 10.1371/journal.pone.0008956 |