| Name | Gastric cancer (A:m6A) |
| Description | Decreased m6A methylation level, by METTL14 downregulation or FTO upregulation, promotes the activation of oncogenic signaling pathways, such as Wnt and PI3K‐Akt and supports GC cell proliferation, migration and invasion. |
| Related RNA reaction | A:m6A |
| Found in RNA | mRNA |
| Modified Transcript | Wnt and PI3K‐Akt pathways and E-chaderin |
| Mapping Technology | |
| Quantification techniques |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| METTL14 | N6-adenosine-methyltransferase non-catalytic subunit | tumor-suppressor | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1023 | Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer. | Cheng Zhang | Cancer Med | [details] | 31243897 | 10.1002/cam4.2360 |