Modomics - A Database of RNA Modifications

Summary:

NameGlioblastoma (A:m6A)
DescriptionDecreased methylation promotes GSCs growth and self-renewal. METTL14 induced methylation protects against GSCs growth and self-renewal
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptADAM19
Mapping TechnologyMeRIP-seq
Quantification techniquesm6A dot blot assay

Enzymes connected to Glioblastoma:

Acronym Full name Enzyme Role Organism Comment
METTL14 N6-adenosine-methyltransferase non-catalytic subunit tumor-suppressor Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1027 m(6)A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of GlioblastomaStem Cells. Cui Q Cell Rep [details] 28297667 10.1016/j.celrep.2017.02.059