| Name | Hepatocellular carcinoma (A:m6A) |
| Description | m6A methylation of pri-miR126 enhances its recogntion by DGCR8 and its subsequent processing to mature miRNA. miR126 plays an important role in tumor metastasis by acting as a tumor suppressor. The downregulation of METTL14 in HCC cells leads to the decreased processing of pri-miR126 thus reducing its tumor-suppressor activity |
| Related RNA reaction | A:m6A |
| Found in RNA | miRNA |
| Modified Transcript | miR126 |
| Mapping Technology | |
| Quantification techniques | m6A dot blot assay, m6A immunoblotting |