Modomics - A Database of RNA Modifications

Summary:

NameHepatocellular carcinoma (A:I)
DescriptionOverexpression of ADAR1 contributes to the alterations in RNA editing patterns, including the editing on FLNB. Moreover, the editing of AZIN1 is responsible for the ADAR1-induced malignant phenotype during ESCC progression
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptFLNB, AZIN1
Mapping Technologydirect sequemcing on PCR products
Quantification techniquesRT-PCR

Enzymes connected to Hepatocellular carcinoma:

Acronym Full name Enzyme Role Organism Comment
ADAR Double-stranded RNA-specific adenosine deaminase oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1050 Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma. Yan-Ru Qin Cancer Res [details] 24302582 10.1158/0008-5472.CAN-13-2545