Name | Hepatocellular carcinoma (A:I) |
Description | Overexpression of ADAR1 contributes to the alterations in RNA editing patterns, including the editing on FLNB. Moreover, the editing of AZIN1 is responsible for the ADAR1-induced malignant phenotype during ESCC progression |
Related RNA reaction | A:I |
Found in RNA | mRNA |
Modified Transcript | FLNB, AZIN1 |
Mapping Technology | direct sequemcing on PCR products |
Quantification techniques | RT-PCR |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
ADAR | Double-stranded RNA-specific adenosine deaminase | oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1050 | Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma. | Yan-Ru Qin | Cancer Res | [details] | 24302582 | 10.1158/0008-5472.CAN-13-2545 |