| Name | Hepatocellular carcinoma (A:I) |
| Description | An increase in RNA editing on AZIN1 neutralizes a key inhibitor of the polyamine synthesis pathway, thereby promoting proliferation in vitro and tumor initiation in vivo. AZIN1 editing is associated with liver cirrhosis |
| Related RNA reaction | A:I |
| Found in RNA | mRNA |
| Modified Transcript | AZIN1 |
| Mapping Technology | RNA-seq |
| Quantification techniques | qRT-PCR |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| ADAR | Double-stranded RNA-specific adenosine deaminase | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1051 | Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma. | Yan Li,Chi Ho Lin,Tim Hon Man Chan,Raymond Kwok Kei Chow,Yangyang Song,Ming Liu,Yun-Fei Yuan,Li Fu,Kar Lok Kong,Lihua Qi,Yan Li,Na Zhang,Amy Hin Yan Tong,Dora Lai-Wan Kwong,Kwan Man,Chung Mau Lo,Si Lok,Daniel G Tenen, | Nat Med | [details] | 23291631 | 10.1038/nm.3043 |