Name | Hepatocellular carcinoma (A:I) |
Description | RNA editing increases and neutralizes a key inhibitor of the polyamine synthesis pathway, thereby promoting proliferation in vitro and increasing tumor initiation and is asscoaited with liver cirrhosis |
Related RNA reaction | A:I |
Found in RNA | mRNA |
Modified Transcript | AZIN1 |
Mapping Technology | RNA-seq |
Quantification techniques | qRT-PCR |
Acronym | Full name | Enzyme Role | Organism |
---|---|---|---|
ADARB1 | Double-stranded RNA-specific editase 1 | oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1051 | Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma. | Leilei Chen | Nat Med | [details] | 23291631 | 10.1038/nm.3043 |