Modomics - A Database of RNA Modifications


NameHepatocellular carcinoma (A:I)
DescriptionRNA editing increases and neutralizes a key inhibitor of the polyamine synthesis pathway, thereby promoting proliferation in vitro and increasing tumor initiation and is asscoaited with liver cirrhosis
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptAZIN1
Mapping TechnologyRNA-seq
Quantification techniquesqRT-PCR

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
ADARB1 Double-stranded RNA-specific editase 1 oncogene Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
1051 Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma. Leilei Chen Nat Med [details] 23291631 10.1038/nm.3043

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