| Name | Non-small cell lung cancer (A:m6A) |
| Description | ALKBH5 is upregulated in the NSCLC tissue and cells. ALKBH5 induces the demethylation of TIMP3 transcript to repress its mRNA stability leading to NSCLC tumor progression |
| Related RNA reaction | A:m6A |
| Found in RNA | mRNA |
| Modified Transcript | TIMP3 |
| Mapping Technology | |
| Quantification techniques | MeRIP-qPCR |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| ALKBH5 | RNA demethylase ALKBH5 | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1095 | N(6)-methyladenosine ALKBH5 promotes non-small cell lung cancer progress byregulating TIMP3 stability. | Zhu Z, Qian Q, Zhao X, Ma L, Chen P | Gene | [details] | 31927006 | 10.1016/j.gene.2020.144348 |