Summary:

NameNon-small cell lung cancer (A:m6A)
DescriptionALKBH5 is upregulated in the NSCLC tissue and cells. ALKBH5 induces the demethylation of TIMP3 transcript to repress its mRNA stability leading to NSCLC tumor progression
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptTIMP3
Mapping Technology
Quantification techniquesMeRIP-qPCR

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
ALKBH5 oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1095 N(6)-methyladenosine ALKBH5 promotes non-small cell lung cancer progress byregulating TIMP3 stability. Zhu Z Gene [details] 31927006 S0378-1119(20)30017-2

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