| Name | Pancreatic cancer (A:m6A) |
| Description | Increased KCNK15-AS1 lncRNA m6A methylation level is negatively correlated with KCNK15-AS1 expression and it sustains the proliferation, invasion and migration of pancreatic cancer cells. Decreased expression of ALKBH5 in pancreatic cancer cell determines an increased methylation of KCNK15-AS1 lncRNA, a decreased KCNK15-AS1 expression and an increased proliferation, migration and invasion of pancreatic cancer cells. |
| Related RNA reaction | A:m6A |
| Found in RNA | lncRNA |
| Modified Transcript | KCNK15-AS1 |
| Mapping Technology | |
| Quantification techniques | MeRIP RT-qPCR |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| ALKBH5 | RNA demethylase ALKBH5 | tumor-suppressor | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1106 | ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation. | Yuan He | Cell Physiol Biochem | [details] | 30032148 | 10.1159/000491915 |