Modomics - A Database of RNA Modifications

Summary:

NameHodgkin lymphoma (A:m1A)
DescriptionThe genes related to migration and cytoskeleton are the target of m1A modification. This epigenetic chaneg cause poor overall survival.
Related RNA reactionA:m1A
Found in RNAmRNA
Modified TranscriptCOL1A2 and COL1A1
Mapping Technologym1A-seq
Quantification techniquesqRT-pcr

Enzymes connected to Hodgkin lymphoma:

Acronym Full name Enzyme Role Organism Comment
ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase oncogene Homo sapiens

Publications:

ID Title Authors Journal Details PubMed Id DOI
1399 Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome. Rosaura Esteve-Puig,Fina Climent,David Piñeyro,Eva Domingo-Domènech,Veronica Davalos,Maite Encuentra,Anna Rea,Nadia Espejo-Herrera,Marta Soler,Miguel Lopez,Vanessa Ortiz-Barahona,Gustavo Tapia,José-Tomás Navarro,Joan Cid,Lourdes Farré,Alberto Villanueva,Isolda Casanova,Ramon Mangues,Pablo Santamarina-Ojeda,Agustín F Fernández,Mario F Fraga,Miguel Angel Piris,Nitzan Kol,Chen Avrahami,Sharon Moshitch-Moshkovitz,Gideon Rechavi,Anna Sureda,Manel Esteller Blood [details] 32915956 -