Summary:

NameHodgkin lymphoma (A:m1A)
DescriptionThe genes related to migration and cytoskeleton are the target of m1A modification. This epigenetic chaneg cause poor overall survival.
Related RNA reactionA:m1A
Found in RNAmRNA
Modified TranscriptCOL1A2 and COL1A1
Mapping Technologym1A-seq
Quantification techniquesqRT-pcr

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1399 Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome. Rosaura Esteve-Puig Blood [details] 32915956 -

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