Name | Systemic Lupus Erythematosus (A:I) |
Description | Up-regulation of ADAR1 may be suppressing the ADAR2 function and results in hypo-editing in PDE8A1 gene transcripts of SLE T cells. |
Related RNA reaction | A:I |
Found in RNA | mRNA |
Modified Transcript | PDE8A1 |
Mapping Technology | RT-PCR |
Quantification techniques | RT-PCR, sequencing |
Acronym | Full name | Enzyme Role | Organism | Comment | Exact modification enzyme yet to be verified. One or more ADAR enzymes involved, putatively. |
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ID | Title | Authors | Journal | Details | ||
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1412 | Altered editing in cyclic nucleotide phosphodiesterase 8A1 gene transcripts of systemic lupus erythematosus T lymphocytes | Robert J Orlowski, | [details] | 18462347 | 10.1111/j.1365-2567.2008.02850.x |