| Name | Systemic Lupus Erythematosus (A:I) |
| Description | Up-regulation of ADAR1 may be suppressing the ADAR2 function and results in hypo-editing in PDE8A1 gene transcripts of SLE T cells. |
| Related RNA reaction | A:I |
| Found in RNA | mRNA |
| Modified Transcript | PDE8A1 |
| Mapping Technology | RT-PCR |
| Quantification techniques | RT-PCR, sequencing |
| Acronym | Full name | Enzyme Role | Organism | Comment | Exact modification enzyme yet to be verified. One or more ADAR enzymes involved, putatively. |
|---|
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1412 | Altered editing in cyclic nucleotide phosphodiesterase 8A1 gene transcripts of systemic lupus erythematosus T lymphocytes | Robert J Orlowski, Kenneth S O'Rourke, Irene Olorenshaw, Gregory A Hawkins, Stefan Maas, Dama Laxminarayana | [details] | 18462347 | 10.1111/j.1365-2567.2008.02850.x |