Modomics - A Database of RNA Modifications

Summary:

NameNeurofibromatosis (C:U)
DescriptionC→U editing of NF1 RNA creates a translational stop codon, potentially leading to premature truncation of neurofibromin
Related RNA reactionC:U
Found in RNAmRNA
Modified TranscriptNF1
Mapping TechnologyRT-PCR
Quantification techniquesRT-PCR, Poisoneed Primer Extension, SSCP

Enzymes connected to Neurofibromatosis:

Acronym Full name Enzyme Role Organism Comment
APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1414 The Neurofibromatosis Type I Messenger RNA Undergoes Base-Modification RNA Editing G R Skuse [details] 8602361 10.1093/nar/24.3.478