ID Card:
Full name:
tRNA-specific adenosine deaminase, chloroplastic
Synonym:
AtTadA
GI:
15221490
Orf:
F14K14.18, F24J5.5
COG:
COG0590
UniProt:
Q9S7I0
Structures:
|
Alpha Fold Predicted Structure:
AF-Q9S7I0-F1
Enzyme type:
deaminase
Position of modification - modification:
t :34 - I
Protein sequence:
MFNTYTNSLQWPIRSRNQQDYCSLLPERSESYKLSKAYTSSRCYCVSSRSSCCCCCSTPSSSSFVKPKVLINPGFVLYGVRQSTLIQWPSFQRRLLVGGGRLMGCEVYSSCDGIRRKNRSFKLRCLEESDECCGGRSCSDDVEAMISFLSEELIDEERKWNLVSRVKEKKKVGNVRKVSVEGSNSYGNGRVSQRVKKPEGFGRRKEIKEDVKLNERYDCEHCGRRKKSSELESESRRGSKLVTGEYIGKSYRGDEEREVRPRRRKSSSCSSYYSLASSGEFESDTEDQEEDVEIYRENVRSSEKKVVDQSAKRLKSRKEASQMHSRKKRDESSTGVDSRYQKQIFEEGENSNQAVTLNQRRRKKFSQTENRVSESTGNYEEDMEIHEVHVNDAETSSQNQKLFNEREDYRVHSIRNDSGNENIESSQHQLKERLETRYSSEDRVSEMRRRTKYSSSQEEGINVLQNFPEVTNNQQPLVEERISKQAGTRRTTEHISESSEIHDIDIRNTYVSQREDQIRNQEVHAGLVSGLQSERKQQDYHIEHNPLQTTQSDRTSVSVSHTSDAVRYTEIQRKSEKRLIGQGSTTAVQSDSKVEKNGAQKEDSRLDHANSKKDGQTTLGLQSYQSKLSEEASSSQSSLMASRTKLQLVDLVSEEMQGSETTLIPPSSQLVSRRSGQSYRTGGVSIQEISHGTSESGYTTAFEHPRAGASVNSQSAGELMGFTSHEDAMGSAHRLEQASEKYVGEFVKKAKHGVINPETEEQRAESNQLKRRDSRRSSGGSGAKGPSDEMWVTDSAQGTPHPGATEGNAAVGNAIFKRNGRSLWNVIADIARLRWGSRAGSPDSSAKPAGRSSPNESVSSATWFSGREHDGSSDDNTKGDKVLPQEAPSLHQVEVGQTSPRSQSEYPGTTKLKQRSERHEGVVSSPSSTILEGGSVSNRMSSTSGNQIVGVDEEEGGNFEFRLPETALTEVPMKLPSRNLIRSPPIKESSESSLTEASSDQNFTVGEGRRYPRMDAGQNPLLFPGRNLRSPAVMEPPVPRPRMVSGSSSLREQVEQQQPLSAKSQEETGSVSADSALIQRKLQRNKQVVRDSFEEWEEAYKVEAERRTVDEIFMREALVEAKKAADTWEVPVGAVLVHDGKIIARGYNLVEELRDSTAHAEMICIREGSKALRSWRLADTTLYVTLEPCPMCAGAILQARVNTLVWGAPNKLLGADGSWIRLFPGGEGNGSEASEKPPPPVHPFHPKMTIRRGVLESECAQTMQQFFQLRRKKKDKNSDPPTPTDHHHHHLPKLLNKMHQVLPFFCL
Comments:
A-to-I tRNA editing enzyme from chloroplasts. This enzyme has an unusual structure in that it harbors a large N-terminal domain of more than 1000 amino acids long which is not required for catalytic activity. Only the C-terminal region displays sequence similarity to the tRNA adenosine deaminase TadA from Escherichia coli. Moreover, AtTadA is imported into the chloroplast in vivo.
Alpha Fold Predicted Structure:
Parsing response... [1048576/1202834]
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Protein sequence:
M
F
N
T
Y
T
N
S
L
Q
W
P
I
R
S
R
N
Q
Q
D
Y
C
S
L
L
P
E
R
S
E
S
Y
K
L
S
K
A
Y
T
S
S
R
C
Y
C
V
S
S
R
S
S
C
C
C
C
C
S
T
P
S
S
S
S
F
V
K
P
K
V
L
I
N
P
G
F
V
L
Y
G
V
R
Q
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Q
W
P
S
F
Q
R
R
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L
V
G
G
G
R
L
M
G
C
E
V
Y
S
S
C
D
G
I
R
R
K
N
R
S
F
K
L
R
C
L
E
E
S
D
E
C
C
G
G
R
S
C
S
D
D
V
E
A
M
I
S
F
L
S
E
E
L
I
D
E
E
R
K
W
N
L
V
S
R
V
K
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K
K
K
V
G
N
V
R
K
V
S
V
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G
S
N
S
Y
G
N
G
R
V
S
Q
R
V
K
K
P
E
G
F
G
R
R
K
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I
K
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D
V
K
L
N
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Y
D
C
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H
C
G
R
R
K
K
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S
E
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E
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S
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G
S
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G
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G
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Y
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G
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R
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R
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R
R
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S
S
S
C
S
S
Y
Y
S
L
A
S
S
G
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F
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D
Q
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D
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N
N
Q
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A
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L
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L
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N
L
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P
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K
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S
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A
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D
Q
N
F
T
V
G
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G
R
R
Y
P
R
M
D
A
G
Q
N
P
L
L
F
P
G
R
N
L
R
S
P
A
V
M
E
P
P
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P
R
P
R
M
V
S
G
S
S
S
L
R
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Q
V
E
Q
Q
Q
P
L
S
A
K
S
Q
E
E
T
G
S
V
S
A
D
S
A
L
I
Q
R
K
L
Q
R
N
K
Q
V
V
R
D
S
F
E
E
W
E
E
A
Y
K
V
E
A
E
R
R
T
V
D
E
I
F
M
R
E
A
L
V
E
A
K
K
A
A
D
T
W
E
V
P
V
G
A
V
L
V
H
D
G
K
I
I
A
R
G
Y
N
L
V
E
E
L
R
D
S
T
A
H
A
E
M
I
C
I
R
E
G
S
K
A
L
R
S
W
R
L
A
D
T
T
L
Y
V
T
L
E
P
C
P
M
C
A
G
A
I
L
Q
A
R
V
N
T
L
V
W
G
A
P
N
K
L
L
G
A
D
G
S
W
I
R
L
F
P
G
G
E
G
N
G
S
E
A
S
E
K
P
P
P
P
V
H
P
F
H
P
K
M
T
I
R
R
G
V
L
E
S
E
C
A
Q
T
M
Q
Q
F
F
Q
L
R
R
K
K
K
D
K
N
S
D
P
P
T
P
T
D
H
H
H
H
H
L
P
K
L
L
N
K
M
H
Q
V
L
P
F
F
C
L
100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 Sequence G H T B S N
Secondary Structure Alphabet
G: 3-turn helix (310 helix) H: α-helix I: 𝝅-helix (5 - turn helix) T: Hydrogen Bonded Turn B: β-sheet S: Bend C: Coil (residues not present in any of the above conformations) N: Not assigned
Download PDB Structures & DSSP Secondary Structures:
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