Modomics - A Database of RNA Modifications

ID Card:

Full name: TLE family member 5, transcriptional modulator
Synonym: GRG5
GI: 23503062
UniProt: Q08117
Alpha Fold Predicted Structure: AF-Q08117-F1



Protein sequence:

MMFPQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSIIRQQLQAHQLSQLQALALPLTPLPVGLQPPSLPAVSAGTGLLSLSALGSQAHLSKEDKNGHDGDTHQEDDGEKSD

Comments:





Alpha Fold Predicted Structure:






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Protein sequence:

M M F P Q S R H S G S S H L P Q Q L K F T T S D S C D R I K D E F Q L L Q A Q Y H S L K L E C D K L A S E K S E M Q R H Y V M Y Y E M S Y G L N I E M H K Q A E I V K R L N G I C A Q V L P Y L S Q E H Q Q Q V L G A I E R A K Q V T A P E L N S I I R Q Q L Q A H Q L S Q L Q A L A L P L T P L P V G L Q P P S L P A V S A G T G L L S L S A L G S Q A H L S K E D K N G H D G D T H Q E D D G E K S D
20406080100120140160180MMFPQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSIIRQQLQAHQLSQLQALALPLTPLPVGLQPPSLPAVSAGTGLLSLSALGSQAHLSKEDKNGHDGDTHQEDDGEKSDSequenceGHTSN

Enter the variants

Position

Original

Variant

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-Q08117-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-Q08117-F1.cif  
DSSP Secondary Structures   Q08117.dssp  





Diseases connected to this enzyme:

Publications: