| Name | Leukemia (xX:Xm) |
| Description | Loss of 2'-O-Me results in decreased leukemia self-renewal potential and reduced colony formation potential. |
| Related RNA reaction | xX:Xm |
| Found in RNA | rRNA |
| Modified Transcript | 18S rRNA (C1703 and G1328) |
| Mapping Technology | |
| Quantification techniques | RT-qPCR |
| Acronym | Full name | Enzyme Role | Organism |
|---|---|---|---|
| DDX21 | DExD-box helicase 21 | oncogene | Homo sapiens |
| FBL | rRNA 2′-O-methyltransferase fibrillarin | oncogene | Homo sapiens |
| TLE5 | TLE family member 5, transcriptional modulator | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1060 | AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia. | Fengbiao Zhou | Nat Cell Biol | [details] | 28650479 | 10.1038/ncb3563 |