Modomics - A Database of RNA Modifications

ID Card:

Full name: tRNA-specific adenosine deaminase subunit TAD2
Complex: Tad2/3
Enzyme type:
Position of modification - modification: t:None - I
Level of experimental evidence: 2
Level of experimental reliability: 2



Protein sequence:

nan

Comments:

The recombinant enzyme consisting of two subunits (BjADAT2 and BjADAT3) can not only perform A-to-I editing of tRNA but also C-to-U and A-to-I deamination of DNA




Reaction Substrate SubstrateType Position (Anti)Codon Modified (Anti)Codon Amino Acid Change Transcript Name Transcript Region Cellular Localization References
A:I tRNA (t) tRNA/tRNA/eukaryotic cytosol 34



Publications:

Title Authors Journal Details PubMed Id DOI
Amphioxus adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U and A-to-I deamination of DNA. Gao Z; Jiang W; Zhang Y; Zhang L; Yi M; Wang H; Ma Z; Qu B; Ji X; Long H; Zhang S Commun Biol [details] 37464027 10.1038/s42003-023-05134-0