Modomics - A Database of RNA Modifications

Reaction details:

Reaction type level 1: decarboxymethylation
Reaction type level 2: dealkylation
Reaction type level 3: group removal
Input group: *C(=O)O
Output group: *[H]
Introduced group name: hydrogen
Introduced group type: hydrogen
Site: extra group
Atom address: C5.N2
Modification level: 2

Enzymes that catalyse this reaction:

Acronym Full name Organism
MnmCD tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase / FAD-dependent cmnm(5)s(2)U34 oxidoreductase Escherichia coli
 

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Publications

Title Authors Journal Details PubMed Id DOI
Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA. Bujnicki JM, Oudjama Y, Roovers M, Owczarek S, Caillet J, Droogmans L RNA [details] 15247431 -