Modomics - A Database of RNA Modifications

IUPAC Name nitrophenylethyl
Protecting group base protection
Deprotection with DBU (non-nucleophillic base)
Synthesis reagent nitrophenylethyl chloride

Protection group:

Can be found in the following building blocks:

1-methylguanosine (BB2) 2140-65-0
2-methylthio-N6-threonyl carbamoyladenosine 24719-82-2
N2,2'-O-dimethylguanosine 135023-21-1
N2,N2-dimethylguanosine 2140-67-2
N2,N2-dimethylguanosine (BB2) 2140-67-2
N2-methylguanosine 2140-77-4
N2-methylguanosine (BB2) 2140-77-4
N6-threonylcarbamoyladenosine 24719-82-2
N6-threonylcarbamoyladenosine (BB3) 24719-82-2


Title Authors Journal Details PubMed Id DOI
Synthesis of the Anticodon Hairpin tRNAfMet Containing N-{[9-(β-D-Ribofuranosyl)-9H-purin-6-yl]carbamoyl}-L-threonine (=N6-{{[(1S,2R)-1-Carboxy-2-hydroxypropyl]amino}carbonyl}adenosine, t6A) Boudou, V., Langridge, J., Van Aerschot, A., Hendrix, C., Millar, A., Weiss, P. and Herdewijn, P. Helvetica Chimica Acta [details] - 10.1002/(SICI)1522-2675(20000119)83:1<152::AID-HLC
The synthesis of 2'-O-[(Triisopropylsilyl)oxy] methyl (TOM) phosphoramidites of methylated ribonucleosides (m1G, m2G, m22G, m1I, m3U, m4C, m6A, m62A) for use in automated RNA solid-phase synthesis HÖBARTNER Claudia ; KREUTZ Christoph ; FLECKER Elke ; OTTENSCHLÄGER Elke ; PILS Werner ; GRUBMAYR Karl ; MICURA Ronald ; Monatshefte fuer Chemie [details] - -
Synthesis of N-Methylated Ribonucleosides for RNA Synthesis Markus Beier, Wolfgang Pfleiderer Helvetica Chimica Acta [details] - 10.1002/hlca.200390205
Synthesis of 2′-O-[(Triisopropylsilyl)oxy]methyl (= tom)-Protected Ribonucleoside Phosphoramidites Containing Various Nucleobase Analogues Porcher S, Pitsch S. HELVETICA CHIMICA ACTA [details] - 10.1002/hlca.200590209