| IUPAC Name | triisopropyloxymethyl |
|---|---|
| Protecting group | 2'-ribose |
| Deprotection | fluoride labile |
| Synthesis reagent | triisopropyloxymethyl chloride |
Protection group:
Can be found in the following building blocks:
| 1-methyladenosine (BB2) | 15763-06-1 |
| 1-methylguanosine (BB3) | 2140-65-0 |
| 1-methylinosine | 2140-73-0 |
| 3-methyluridine | 2140-69-4 |
| 5-methylcytidine (BB3) | 2140-61-6 |
| 5-methyluridine (BB2) | 1463-10-1 |
| N2,N2-dimethylguanosine (BB2) | 2140-67-2 |
| N2,N2-dimethylguanosine (BB3) | 2140-67-2 |
| N2-methylguanosine | 2140-77-4 |
| N2-methylguanosine (BB3) | 2140-77-4 |
| N4-methylcytidine | 10578-79-7 |
| N6,N6,2'-O-trimethyladenosine | 30891-53-3 |
| N6-acetyladenosine (BB1) | 16265-37-5 |
| N6-isopentenyladenosine | 7724-76-7 |
| N6-isopentenyladenosine (BB3) | 7724-76-7 |
| N6-methyladenosine | 1867-73-8 |
| N6-methyladenosine (BB4) | 1867-73-8 |
| N6-threonylcarbamoyladenosine (BB3) | 24719-82-2 |
| dihydrouridine (BB2) | 5627-05-4 |
| inosine (BB2) | 58-63-9 |
| pseudouridine (BB3) | 1445-07-4 |
| wybutosine | 55196-46-8 |
Publications
| Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|
| The synthesis of 2'-O-[(Triisopropylsilyl)oxy] methyl (TOM) phosphoramidites of methylated ribonucleosides (m1G, m2G, m22G, m1I, m3U, m4C, m6A, m62A) for use in automated RNA solid-phase synthesis | HÖBARTNER Claudia ; KREUTZ Christoph ; FLECKER Elke ; OTTENSCHLÄGER Elke ; PILS Werner ; GRUBMAYR Karl ; MICURA Ronald ; | Monatshefte fuer Chemie | [details] | - | - |
| Synthesis of 2′-O-[(Triisopropylsilyl)oxy]methyl (= tom)-Protected Ribonucleoside Phosphoramidites Containing Various Nucleobase Analogues | Porcher S, Pitsch S. | HELVETICA CHIMICA ACTA | [details] | - | 10.1002/hlca.200590209 |