Modomics - A Database of RNA Modifications

General Data

RNA Type tRNA
SOTerm None
Original Source 3TRA_A
Secondary Structure (((((((..((((....[...)))).(((((.......)))))....((((((.].)..)))))))))))).
Sequence (UNICHARACTER ENCODING) UCCGUGAUAGUUPAADGGDCAGAAUGGGCGCPUGUCKCGUGCCAGAU?GGGGTPCAAUUCCCCGUCGCGGAG
Sequence (SHORT NAMES ENCODING) UCCGUGAUAGUUpYAApDGGpDCAGAAUGGGCGCpYUGUCpm1GCGUGCCAGAUpm5CGGGGpm5UpYCAAUUCCCCGUCGCGGAG
Sequence (MODOMICS CODE ENCODING) UCCGUGAUAGUU2000009551UAA2000008551UGG2000008551UCAGAAUGGGCGC2000009551UUGUC2000001551GCGUGCCAGAU2000005551CGGGG2000005551U2000009551UCAAUUCCCCGUCGCGGAG
Consensus Secondary Structure .(((((((..((((......[....)))).(((((.......)))))........................(((((..]....))))))))))))....
Alignment with Modification -UCCGUGAUAGUUPAAD--GGDC-AGAAUGGGCGCPUGUCKCGUGCCAGAU--------------------?GGGGTPCAAUUCCCCGUCGCGGAG---

Score Table

Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.
Method Classification Score
Multiple direct experimental evidence 1
Direct experimental evidence 2
Inferred based on indirect experimental evidence 3
Predicted computationally 4
Evidence not yet annotated (Unknown) 5
Irrelevant 6

RNA-2D Representation

RNA Secondary Structure

RNA Consensus Secondary Structure

Modification Positions

Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.

Position in the alignment 13 16 20 32 37 49 54 55
Position in the sequence 13 16 19 32 37 48 53 54
Modification positions Y D D Y m1G m5C m5U Y
Level of Experimental Evidence 2 2 2 2 2 2 2 2
Level of Experimental Reliability 2 2 2 2 2 2 2 2
Source RCSB RCSB RCSB RCSB RCSB RCSB RCSB RCSB