Modomics - A Database of RNA Modifications

General Data

RNA Type tRNA
SOTerm SO:0000261
Original Source tdbR00000116
Secondary Structure (((((((..((((....[..)))).(((((.......)))))....(((((..]....))))))))))))....
Sequence (UNICHARACTER ENCODING) GCGGGUGUAGUUUAGUGGDAAAACCUCAGCCU!CCAAGCUGAUGUCGUGAGTPCGAUUCUCAUCACCCGCUCCA
Sequence (SHORT NAMES ENCODING) GCGGGUGUAGUUUAGUGGpDAAAACCUCAGCCUpcmnm5UCCAAGCUGAUGUCGUGAGpm5UpYCGAUUCUCAUCACCCGCUCCA
Sequence (MODOMICS CODE ENCODING) GCGGGUGUAGUUUAGUGG2000008551UAAAACCUCAGCCU2000051551UCCAAGCUGAUGUCGUGAG2000005551U2000009551UCGAUUCUCAUCACCCGCUCCA
Consensus Secondary Structure .(((((((..((((......[....)))).(((((.......)))))........................(((((..]....))))))))))))....
Alignment with Modification -GCGGGUGUAGUUUAGU--GGD--AAAACCUCAGCCU!CCAAGCUGAUGUC--------------------GUGAGTPCGAUUCUCAUCACCCGCUCCA

Score Table

Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.
Method Classification Score
Multiple direct experimental evidence 1
Direct experimental evidence 2
Inferred based on indirect experimental evidence 3
Predicted computationally 4
Evidence not yet annotated (Unknown) 5
Irrelevant 6

RNA-2D Representation

RNA Secondary Structure

RNA Consensus Secondary Structure

Modification Positions

Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.

Position in the alignment 20 34 54 55
Position in the sequence 19 33 52 53
Modification positions D cmnm5U m5U Y
Level of Experimental Evidence 5 5 5 5
Level of Experimental Reliability 5 5 5 5
Source MODOMICS MODOMICS MODOMICS MODOMICS