Modomics - A Database of RNA Modifications

General Data

RNA Type tRNA
SOTerm SO:0000264
Original Source tdbR00000225
Secondary Structure (((((((..(((......[....))).(((((.......)))))(((((....))))).(((((..]....))))))))))))....
Sequence (UNICHARACTER ENCODING) GGGCAAGUGGCGGAAUDGGDAGACGCAGCAGACUCAAHAPCUGCCGCUAGCGAUAGUGUGUGGGTPCGAGUCCCACCUUGCCCACCA
Sequence (SHORT NAMES ENCODING) GGGCAAGUGGCGGAAUpDGGpDAGACGCAGCAGACUCAAxAApYCUGCCGCUAGCGAUAGUGUGUGGGpm5UpYCGAGUCCCACCUUGCCCACCA
Sequence (MODOMICS CODE ENCODING) GGGCAAGUGGCGGAAU2000008551UGG2000008551UAGACGCAGCAGACUCAA2000000999AA2000009551UCUGCCGCUAGCGAUAGUGUGUGGG2000005551U2000009551UCGAGUCCCACCUUGCCCACCA
Consensus Secondary Structure .(((((((..((((......[....)))).(((((.......)))))........................(((((..]....))))))))))))....
Alignment with Modification -GGGCAAGUGGCGGAAUD-GGDA-GACGCAGCAGACUCAAHAPCUGCCGCUAGCGAUAGUGU---------GUGGGTPCGAGUCCCACCUUGCCCACCA

Score Table

Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.
Method Classification Score
Multiple direct experimental evidence 1
Direct experimental evidence 2
Inferred based on indirect experimental evidence 3
Predicted computationally 4
Evidence not yet annotated (Unknown) 5
Irrelevant 6

RNA-2D Representation

RNA Secondary Structure

RNA Consensus Secondary Structure

Modification Positions

Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.

Position in the alignment 17 20 37 39 54 55
Position in the sequence 17 20 38 40 65 66
Modification positions D D xA Y m5U Y
Source MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS

Modification Annotation

Table containing the data present in the literature relating to the modification positions present in the RNA sequences. Some of the modified residuals may differ from the modifications originally present in MODOMICS. It follows the same format as the previous table. The table reports the scores that have been associated to the modified nucleotides so to have an estimation of the reliability of their presence.
Position in the alignment 17 20 37 39 54 55
Position in the sequence 17 20 38 40 65 66
Source: 6780549 D D xA Y m5U Y
Level of Experimental Reliability 3 3 3 3 3 3
Level of Experimental Evidence 3 3 3 3 3 3