Modomics - A Database of RNA Modifications

General Data

RNA Type tRNA
SOTerm SO:0000264
Original Source tdbR00000257
Secondary Structure (((((((..(((.....[.....)))((((((.......))))))((((....))))..(((((..]....))))))))))))....
Sequence (UNICHARACTER ENCODING) GUCAGGAUGLCMGAGDGGDCXAAGGCRCCAGACU.AAKPPCUGGJCUUCGAAAGAGGG?GUGGGTPCAѢAUCCCACUUCUGACACCA
Sequence (SHORT NAMES ENCODING) GUCAGGAUGpm2GCpac4CGAGpDGGpDCpacp3UAAGGCpm2,2GCCAGACUNAApm1GpYpYCUGGpUmCUUCGAAAGAGGGpm5CGUGGGpm5UpYCApm1AAUCCCACUUCUGACACCA
Sequence (MODOMICS CODE ENCODING) GUCAGGAUG2000002551GC2000042551CGAG2000008551UGG2000008551UC2000030551UAAGGC2000022551GCCAGACU2000000000NAA2000001551G2000009551U2000009551UCUGG2000090551UCUUCGAAAGAGGG2000005551CGUGGG2000005551U2000009551UCA2000001551AAUCCCACUUCUGACACCA
Consensus Secondary Structure .(((((((..((((......[....)))).(((((.......)))))........................(((((..]....))))))))))))....
Alignment with Modification -GUCAGGAUGLCMGAGD--GGDCXAAGGCRCCAGACU.AAKPPCUGGJCUUCGAAAGAGGG?---------GUGGGTPCAѢAUCCCACUUCUGACACCA

Score Table

Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.
Method Classification Score
Multiple direct experimental evidence 1
Direct experimental evidence 2
Inferred based on indirect experimental evidence 3
Predicted computationally 4
Evidence not yet annotated (Unknown) 5
Irrelevant 6

RNA-2D Representation

RNA Secondary Structure

RNA Consensus Secondary Structure

Modification Positions

Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.

Position in the alignment 10 12 16 20 20B 26 34 37 38 39 44 45M 54 55 58
Position in the sequence 10 12 16 19 21 27 35 38 39 40 45 59 65 66 69
Modification positions m2G ac4C D D acp3U m2,2G N m1G Y Y Um m5C m5U Y m1A
Level of Experimental Evidence 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
Level of Experimental Reliability 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
Source MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS