Modomics - A Database of RNA Modifications

General Data

RNA Type tRNA
SOTerm SO:0000269
Original Source None
Secondary Structure .(((((((..((((...........)))).(((((.......)))))........................(((((.......))))))))))))....
Sequence (UNICHARACTER ENCODING) GGGGGGUUACUCAAGAGGCUGAAGAGGACGGUU5GCU6AAAUCGU4AG7UCGGGAAACCGGCGCGAGGGUUCGAAUCCCUUACCCCCCU
Sequence (SHORT NAMES ENCODING) GGGGGGUUACUCAAGAGGCUGAAGAGGACGGUUpmo5UGCUpt6AAAAUCGUps4UAGpm7GUCGGGAAACCGGCGCGAGGGUUCGAAUCCCUUACCCCCCU
Sequence (MODOMICS CODE ENCODING) GGGGGGUUACUCAAGAGGCUGAAGAGGACGGUU2000501551UGCU2000062551AAAAUCGU2000074551UAG2000007551GUCGGGAAACCGGCGCGAGGGUUCGAAUCCCUUACCCCCCU
Consensus Secondary Structure .(((((((..((((......[....)))).(((((.......)))))........................(((((..]....))))))))))))....
Alignment with Modification -GGGGGGUUACUCAAGA--GGCUGAAGAGGACGGUU5GCU6AAAUCGU4AG7UCGGGAAACCGGCGC----GAGGGUUCGAAUCCCUUACCCCCCU---

Score Table

Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.
Method Classification Score
Multiple direct experimental evidence 1
Direct experimental evidence 2
Inferred based on indirect experimental evidence 3
Predicted computationally 4
Evidence not yet annotated (Unknown) 5
Irrelevant 6

RNA-2D Representation

RNA Secondary Structure

RNA Consensus Secondary Structure

Modification Positions

Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.

Position in the alignment 33 37 45 45C
Position in the sequence 34 38 46 49
Modification positions mo5U t6A s4U m7G
Level of Experimental Evidence 5 5 5 5
Level of Experimental Reliability 5 5 5 5
Source MODOMICS MODOMICS MODOMICS MODOMICS