Modomics - A Database of RNA Modifications


NameGlioblastoma (A:m1A)
DescriptionTRM6/61 regulates the translation of a subset of mRNAs encoding proteins that play role in cancer.
Related RNA reactionA:m1A
Found in RNAtRNA
Modified Transcriptinitiator methionyl-tRNA (tRNAiMet)
Mapping Technology
Quantification techniquesqRT-PCR

Enzymes connected to Glioblastoma:

Acronym Full name Enzyme Role Organism Comment
Trmt6 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 oncogene Homo sapiens
Trmt61A tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A oncogene Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
1032 TRM6/61 connects PKCĪ± with translational control through tRNAi(Met) stabilization: impact on tumorigenesis. F Macari Oncogene [details] 26234676 10.1038/onc.2015.244