Name | Severe epilepsy (A:I) |
Description | RNA editing in GluR-B is essential for brain development to avoid the alteration of calcium permeability which affects mice seizure and survival |
Related RNA reaction | A:I |
Found in RNA | mRNA |
Modified Transcript | AMPAR GluA2 |
Mapping Technology | |
Quantification techniques | RT-PCR |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
ADARB1 | Double-stranded RNA-specific editase 1 | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1119 | Early-onset epilepsy and postnatal lethality associated with an editing-deficientGluR-B allele in mice. | Brusa R | Science | [details] | 7502080 | 10.1126/science.270.5242.1677 |