Summary:

NameSpinal Cord Injury (A:I)
DescriptionThe reduced editing at the R/G site of glutamate receptor subunits (GluRs) is likely to reduce post-synaptic excitatory responses to glutamate, thus duce post-synaptic excitatory responses to glutamate, thus limiting the progression of cell death.
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptGLUR3
Mapping Technologysequencing of RT-PCR product
Quantification techniquesRT-PCR

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
ADARB1 Double-stranded RNA-specific editase 1 Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1120 Acute spinal cord injury persistently reduces R/G RNA editing of AMPA receptors. Alessandro Barbon J Neurochem [details] 20456005 10.1111/j.1471-4159.2010.06767.x

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