| Name | Hepatocellular carcinoma (A:I) |
| Description | Hyper-editing of FLNB is closely associated with HCC pathogenesis. ADAR1 overexpression increases risk of liver cirrhosis and postoperative recurrence. ADAR1 hyper editing is associated with a poor prognosis |
| Related RNA reaction | A:I |
| Found in RNA | mRNA |
| Modified Transcript | FLNB |
| Mapping Technology | direct sequemcing on PCR products |
| Quantification techniques | RT-PCR |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| ADARB1 | Double-stranded RNA-specific editase 1 | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1014 | A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma. | Chi Ho Lin,Lihua Qi,Jing Fei,Yan Li,Kol Jia Yong,Ming Liu,Yangyang Song,Raymond Kwok Kei Chow,Vanessa Hui En Ng,Yun-Fei Yuan,Daniel G Tenen,Xin-Yuan Guan, | Gut | [details] | 23766440 | 10.1136/gutjnl-2012-304037 |