| Name | Esophageal squamous cell carcinoma (A:I) |
| Description | ADARB1 is downregulated in In Esophageal Squamous Cell Carcinoma (ESCC). In normal tissue, ADARB1 suppresses tumor growth and induces apoptosis by editing and stabilizing IGFBP7. |
| Related RNA reaction | A:I |
| Found in RNA | mRNA |
| Modified Transcript | IGFBP7 |
| Mapping Technology | RNA-seq |
| Quantification techniques | RT-PCR |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| ADARB1 | Double-stranded RNA-specific editase 1 | tumor-suppressor | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1015 | ADAR2 functions as a tumor suppressor via editing IGFBP7 in esophageal squamous cell carcinoma. | Xiao-Yu Liao,Jiang-Bo Zhang,Fang Wang,Hai-De Qin,Lanjun Zhang,Yin Yao Shugart,Yi-Xin Zeng, | Int J Oncol | [details] | 28035363 | 10.3892/ijo.2016.3823 |