Name | Glioblastoma (A:I) |
Description | Reduction of RNA editing at the Q/R site of the GluRB induces loss of Ca2+ homeostasis suggests a role for RNA editing in tumor progression and may provide a molecular model explaining the occurrence of epileptic seizures in association with malignant gliomas. |
Related RNA reaction | A:I |
Found in RNA | mRNA |
Modified Transcript | GRIA2 (GLUR-B) |
Mapping Technology | RT-PCR |
Quantification techniques | RT-PCR, sequencing |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
ADARB1 | Double-stranded RNA-specific editase 1 | None | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
969 | Underediting of glutamate receptor GluR-B mRNA in malignant gliomas. | Maas S | Proc Natl Acad Sci U S A | [details] | 11717408 | 251531398 |