Name | Hepatocellular carcinoma (A:I) |
Description | Hypo-editing of COPA is closely associated with HCC pathogenesis. ADAR2 downregulation increases the risk of liver cirrhosis and postoperative recurrence. It is associated withpoor prognoses |
Related RNA reaction | A:I |
Found in RNA | mRNA |
Modified Transcript | COPA |
Mapping Technology | direct sequencing on PCR product |
Quantification techniques | DSGene quantification |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
ADARB1 | Double-stranded RNA-specific editase 1 | tumor-suppressor | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1014 | A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma. | Tim Hon Man Chan | Gut | [details] | 23766440 | 10.1136/gutjnl-2012-304037 |