Summary:

NameHepatocellular carcinoma (A:I)
DescriptionHypo-editing of COPA is closely associated with HCC pathogenesis and ADAR2 downregulation increased risk of liver cirrhosis and postoperative recurrence and had poor prognoses
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptCOPA
Mapping Technologydirect sequencing on PCR product
Quantification techniquesDSGene quantification

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
ADARB1 Double-stranded RNA-specific editase 1 tumor-suppressor Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1014 A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma. Tim Hon Man Chan Gut [details] 23766440 10.1136/gutjnl-2012-304037

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