| Name | Amiothrophic Lateral Sclerosis (A:I) |
| Description | Defect in the editing of the messenger RNA encoding the GluR2 subunit of glutamate AMPA receptors in ALS patients |
| Related RNA reaction | A:I |
| Found in RNA | mRNA |
| Modified Transcript | GRIA2 |
| Mapping Technology | RT-PCR |
| Quantification techniques | RT-PCR, Restriction Digestion |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| ADARB1 | Double-stranded RNA-specific editase 1 | None | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1402 | Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis | H Takuma | 1999-02-01 | [details] | 10589532 | 10.1002/1531-8249(199912)46:6<806::aid-ana2>3.0.co;2-s |