| Name | Amiothrophic Lateral Sclerosis (A:I) |
| Description | The inefficient GluA2 Q/R site-editing by ADAR2 is one cause of motor neuron death in ALS. |
| Related RNA reaction | A:I |
| Found in RNA | mRNA |
| Modified Transcript | GRIA2 |
| Mapping Technology | RT-PCR |
| Quantification techniques | RT-PCR, Restriction Digestion, sequencing |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| ADARB1 | Double-stranded RNA-specific editase 1 | None | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1403 | Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons | Takuto Hideyama | [details] | 22226999 | 10.1016/j.nbd.2011.12.033 |