Modomics - A Database of RNA Modifications

Reaction details:

Reaction type level 1: deamination
Reaction type level 2: NH2/O exchange
Reaction type level 3: group exchange
Input group: NH2
Output group: *=O
Introduced group name: oxo
Introduced group type: oxo
Site: base/endocyclic
Atom address: C4
Modification level: 0

Enzymes that catalyse this reaction:

Acronym Full name Organism
AICDA Single-stranded DNA cytosine deaminase Homo sapiens
APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 Homo sapiens
CDAT8 tRNA-specific cytidine deaminase Methanopyrus kandleri
 

Image with reaction


Image with reaction

Image with reaction

Publications

Title Authors Journal Details PubMed Id DOI
A cytidine deaminase edits C to U in transfer RNAs in Archaea. Randau L, Stanley BJ, Kohlway A, Mechta S, Xiong Y, Soll D Science [details] 19407206 -