Modomics - A Database of RNA Modifications

General Data

RNA Type tRNA
SOTerm SO:0000258
Original Source tdbR00000173
Secondary Structure (((((((..((((.....[...)))).(((((.......))))).....(.(((..]....))).))))))))....
Sequence (UNICHARACTER ENCODING) GGCCCAUUALCUCAGDDGGDNAGAGCRPCGUGCUIAU6ACGCGAAG7U?G?GGGTPCGѢUCCCCUCAUGGGCCACCA
Sequence (SHORT NAMES ENCODING) GGCCCAUUApm2GCUCAGpDpDGGpDxUAGAGCpm2,2GpYCGUGCUpIAUpt6AACGCGAAGpm7GUpm5CGpm5CGGGpm5UpYCGpm1AUCCCCUCAUGGGCCACCA
Sequence (MODOMICS CODE ENCODING) GGCCCAUUA2000002551GCUCAG2000008551U2000008551UGG2000008551U2000000999UAGAGC2000022551G2000009551UCGUGCU2000009551AAU2000062551AACGCGAAG2000007551GU2000005551CG2000005551CGGG2000005551U2000009551UCG2000001551AUCCCCUCAUGGGCCACCA
Consensus Secondary Structure .(((((((..((((......[....)))).(((((.......)))))........................(((((..]....))))))))))))....
Alignment with Modification -GGCCCAUUALCUCAGDD-GGDN-AGAGCRPCGUGCUIAU6ACGCGAAG7U?-------------------G?GGGTPCGѢUCCCCUCAUGGGCCACCA

Score Table

Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.
Method Classification Score
Multiple direct experimental evidence 1
Direct experimental evidence 2
Inferred based on indirect experimental evidence 3
Predicted computationally 4
Evidence not yet annotated (Unknown) 5
Irrelevant 6

RNA-2D Representation

RNA Secondary Structure

RNA Consensus Secondary Structure

Modification Positions

Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.

Position in the alignment 10 16 17 20 20A 26 27 34 37 45A 45C 50 54 55 58
Position in the sequence 10 16 17 20 21 27 28 35 38 47 49 51 55 56 59
Modification positions m2G D D D xU m2,2G Y I t6A m7G m5C m5C m5U Y m1A
Level of Experimental Evidence 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
Level of Experimental Reliability 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
Source MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS