| Name | Leukemia (A:m6A) |
| Description | Mutations found in m6A regulatory genes are associated with lower OS and EFS rates in patients with AML ( Acute myeloid Leukemia) and presence of p53 mutations. |
| Related RNA reaction | A:m6A |
| Modified Transcript | |
| Mapping Technology | |
| Quantification techniques |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| ALKBH5 | RNA demethylase ALKBH5 | oncogene/tumor-suppressor | Homo sapiens | |
| FTO | Alpha-ketoglutarate-dependent dioxygenase FTO | oncogene/tumor-suppressor | Homo sapiens | |
| METTL14 | N6-adenosine-methyltransferase non-catalytic subunit | oncogene/tumor-suppressor | Homo sapiens | |
| METTL3 | N6-adenosine-methyltransferase 70 kDa subunit | oncogene/tumor-suppressor | Homo sapiens | |
| YTHDF1 | YTH N6-methyladenosine RNA binding protein 1 | oncogene/tumor-suppressor | Homo sapiens | |
| YTHDF2 | YTH N6-methyladenosine RNA binding protein 2 | oncogene/tumor-suppressor | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1062 | Genetic alterations of mA regulators predict poorer survival in acute myeloid leukemia. | Amy D Marshall,John E J Rasko, | J Hematol Oncol | [details] | 28153030 | 10.1186/s13045-017-0410-6 |