Modomics - A Database of RNA Modifications

Reaction details:

Reaction type level 1: methylation
Reaction type level 2: alkylation
Reaction type level 3: group addition
Input group: H
Output group: *C
Introduced group name: methyl
Introduced group type: hydrocarbon
Site: sugar
Atom address: 2′O
Modification level: 1

Enzymes that catalyse this reaction:

Acronym Full name Organism
CMTR1 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Homo sapiens
CMTr2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 Homo sapiens
FBL rRNA 2′-O-methyltransferase fibrillarin Homo sapiens
Nop1 rRNA 2′-O-methyltransferase fibrillarin Saccharomyces cerevisiae
Nsr rRNA (adenosine-2'-O-)-methyltransferase Streptomyces actuosus
Trm13 tRNA-2′-O-methyltransferase TRM13 Saccharomyces cerevisiae
Tsr rRNA (adenosine-2'-O-)-methyltransferase Streptomyces cyaneus

Image with reaction