Modomics - A Database of RNA Modifications

Reaction details:

Reaction type level 1: methylation
Reaction type level 2: alkylation
Reaction type level 3: group addition
Input group: H
Output group: *C
Introduced group name: methyl
Introduced group type: hydrocarbon
Site: sugar
Atom address: 2ʹO
Modification level: None

Enzymes that catalyse this reaction:

Acronym Full name Organism
FBL rRNA 2′-O-methyltransferase fibrillarin Homo sapiens
FTSJ1 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase Homo sapiens
FlpA Fibrillarin-like rRNA/tRNA 2′-O-methyltransferase Sulfolobus solfataricus
FlpA Fibrillarin-like rRNA/tRNA 2′-O-methyltransferase Methanocaldococcus jannaschii
FlpA Fibrillarin-like rRNA/tRNA 2′-O-methyltransferase Pyrococcus horikoshii
FlpA Fibrillarin-like rRNA/tRNA 2′-O-methyltransferase Archaeoglobus fulgidus
Hen1 Methyltransferase type 12 Clostridium thermocellum
Hen1 Small RNA 2′-O-methyltransferase Arabidopsis thaliana
Nop1 rRNA 2′-O-methyltransferase fibrillarin Saccharomyces cerevisiae
LARP7 La ribonucleoprotein 7, transcriptional regulator Homo sapiens
NPM1 nucleophosmin 1 Homo sapiens
 

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Any residue (A, C, G, U)


Image with reaction

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Any residue (A, C, G, U)