Modomics - A Database of RNA Modifications

Reaction details:

Reaction type level 1: methylation
Reaction type level 2: alkylation
Reaction type level 3: group addition
Input group: H
Output group: *C
Introduced group name: methyl
Introduced group type: hydrocarbon
Site: base/endocyclic
Atom address: C5
Modification level: 1

Enzymes that catalyse this reaction:

Acronym Full name Organism
RlmC Ribosomal RNA large subunit methyltransferase C Escherichia coli
RlmC 23S rRNA (uracil(747)-C(5))-methyltransferase Pyrococcus abyssi
RlmCD 23S rRNA (uracil-C(5))-methyltransferase RlmCD Bacillus subtilis
RlmD Ribosomal RNA large subunit methyltransferase D Escherichia coli
RlmFO 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmFO Mycoplasma capricolum
Trm2 tRNA (uracil-5-)-methyltransferase Saccharomyces cerevisiae
TrmA tRNA (uridine(54)-C5)-methyltransferase Escherichia coli
TrmFO Methylenetetrahydrofolate--tRNA-(uracil-54-)-methyltransferase TrmFO Bacillus subtilis
TrmFO Methylenetetrahydrofolate-tRNA-(uracil-54-)-methyltransferase TrmFO Thermus thermophilus
TrmU54 tRNA (uracil(54)-C(5))-methyltransferase Pyrococcus abyssi

Image with reaction

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